Repbase Reports

2010, Volume 10, Issue 4
April 30, 2010
Copyright © 2001-2016 - Genetic Information Research Institute
ISSN# 1534-830X
Page 647

Academ-1_SP

This family belongs to the Academ superfamily of DNA transposons.

Submitted:
30-Apr-2010
Accepted:
30-APR-2010
Key Words:
Academ; DNA transposon; Transposable Element; Academ-1_SP
Source:
Strongylocentrotus purpuratus
Organism:
Strongylocentrotus purpuratus
Taxonomy:
Eukaryota; Metazoa; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Echinoida; Strongylocentrotidae; Strongylocentrotus
[1] Authors:
Kapitonov,V.V. and Jurka,J.
Title:
Academ - a novel superfamily of eukaryotic DNA transposons.
Journal:
Repbase Reports 10(4), 647-647 (2010)
Abstract:
Academ is a novel superfamily of DNA transposons that populate genomes of metazoans, including cnidarians, insects, sea urchins, lancelet, and fish. The autonomous Academ transposons encode a ~1500-aa protein composed of a novel Academ transposase domain, which is not similar to transposases encoded by any other transposable elements reported previously, the XPG domain, and the putative Cys8 zinc finger. The XPG domain is structurally and functionally related to FEN-1; divalent metal ion-dependent exo- and endonuclease, and bacterial and bacteriophage 5'-3' exonucleases. The Cys8 zinc finger is a conserved set of eight cysteines: Cys-X-Cys-X3,4-Cys-X3,10-Cys-X-Cys-X6-Cys-X3-Cys-X1,2-Cys. Academ transposons generate 3-bp target site duplications and contain terminal inverted repeats whose length varies from 6 to 530 bp. Usually, Academ transposons have the 5'-TAG and CTA-3' termini. Academ-1_SP is a young family. The consensus was derived from multiple alignment of several copies >95% identical to it. Imperfect TIRs are 13 bp long.
Derived:
[1] (Consensus)
Download Sequence - Format:
IG, EMBL, FASTA
References:

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