Repbase Reports

2007, Volume 7, Issue 9
September 30, 2007
Copyright © 2001-2016 - Genetic Information Research Institute
ISSN# 1534-830X
Page 775

Chapaev-1_ACa

Autonomous DNA transposon - a consensus sequence.

Submitted:
30-Sep-2007
Accepted:
30-Sep-2007
Key Words:
Chapaev; DNA transposon; Transposable Element; Chapaev-1_ACa
Source:
Aplysia californica
Organism:
Aplysia californica
Taxonomy:
Eukaryota; Metazoa; Mollusca; Gastropoda; Orthogastropoda; Apogastropoda; Heterobranchia; Euthyneura; Opisthobranchia; Anaspidea; Aplysioidea; Aplysiidae; Aplysia
[1] Authors:
Kapitonov,V.V. and Jurka,J.
Title:
Chapaev - a novel superfamily of DNA transposons.
Journal:
Repbase Reports 7(9), 775-775 (2007)
Abstract:
Chapaev-1_ACa is a very young family of DNA transposons. The genome contains several copies of Chapaev-1_ACa that are less then 1% divergent from the consensus sequence. Chapaev-1_ACa belongs to the Chapaev superfamily. Hallmarks of the Chapaev transposons are 4-bp target-site duplications, terminal inverted repeats with the conserved '5-CAC and GTG-3' termini, and the Chapaev transposase. The Chapaev transposase is characterized by the conserved D-x(60-80)-D-x(220-290)-E catalytic triad. Chapaev transposons populate genomes of different animals, including sea urchin Strongylocentotus purpuratus, amphioxus Branchiostoma floridae, starlet sea anemone Nematostella vectensis, sea hare mollusc Aplysia californica, mosquitoes Aedes aegypti and Culex pipiens, and nematode Caenorhabditis elegans. The N-terminal portion of Chapaev transposase in Chapaev-1_ACa, Chapaev-2_ACa, Chapaev-3_ACa, Chapaev-1_BF, Chapaev-2_BF, Chapaev-1_NV, Chapaev-2_NV, Chapaev-3_NV, and Chapaev-1_SP is similar to the N-terminal portion of RAG1 (100-370 aa in the human RAG1). It includes a novel type of zinc finger, called Chapa: H-X7-C-R-X-C-G-X35-D-X4-H-X4-C-X2-C-W-Xn-C-X2-C-X8-G. In the amphioxus and anemone Chapaevs, the N-terminal portion contains also the RING finger motif. Some Chapaev transposases (e.g. Chapaev-2_ACa) show low similarity to the RAG1 core.
Derived:
[1] (Consensus)
Download Sequence - Format:
IG, EMBL, FASTA
References:

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