Repbase Reports

2007, Volume 7, Issue 2
February 28, 2007
Copyright © 2001-2016 - Genetic Information Research Institute
ISSN# 1534-830X
Page 119

Kolobok-2_XT

A family of autonomous Kolobok transposons - a consensus.

Submitted:
27-Feb-2007
Accepted:
28-Feb-2007
Key Words:
Kolobok; DNA transposon; Interspersed Repeat; nonautonomous; non-autonomous; Passage-2_XT; Kolobok-2_XT
Source:
Xenopus tropicalis
Organism:
Xenopus tropicalis
Taxonomy:
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
[1] Authors:
Kapitonov,V.V. and Jurka,J.
Title:
Kolobok, a novel superfamily of eukaryotic DNA transposons.
Journal:
Repbase Reports 7(2), 119-119 (2007)
Abstract:
DNA transposons from the Kolobok superfamily are characterized by the TTAA target site duplications, which are identical to these produced by the piggyBac transposons. However, while piggyBac transposons have 5'-YY termini, Kolobok transposons have 5'-RR termini. Autonomous Kolobok transposons encode the Kolobok transposase, which is not similar to any other proteins in eukaryotes and prokaryotes. Kolobok transposons are widely spread in different eukaryotic species, including protists, fungi, invertebrates, and vertebrates. Kolobok-2_XT is a consensus sequence of a family of autonomous Kolobok transposons that were active in the frog genome in a last few million years. The Kolobok-2_XT consensus sequence codes for the intronless 783-aa transposase composed of the THAP DNA-binding domain and catalytic "DDE" domain, which is conserved in all Kolobok transposases. In addition to the transpose, a second protein, Kolobok-2_XT2p, is encoded by Kolobok-2_XT. This protein is also conserved in diverse Kolobok transposons from vertebrates, chordates, and cnidarians (see comments for Kolobok-1_XT).
Derived:
[1] (Consensus)
Download Sequence - Format:
IG, EMBL, FASTA
References:

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