Repbase Reports |
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| 2002, Volume 2, Issue 6 |
| June 30, 2002 |
| Copyright © 2001-2016 - Genetic Information Research Institute |
| ISSN# 1534-830X |
| Page 18 |
I-1_DR |
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I-1_DR is a non-LTR retrotransposon from the I clade. |
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Submitted: 30-Jun-2002 |
Accepted: 30-Jun-2002 |
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Key Words: Non-LTR retrotransposon; endonuclease; reverse transcriptase; RNaseH; I clade; I-1_DR |
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Source: Danio rerio |
Organism: Danio rerio |
Taxonomy: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Actinopterygii; Neopterygii; Teleostei; Euteleostei; Ostariophysi; Cypriniformes; Cyprinoidea; Cyprinidae; Rasborinae; Danio |
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| [1] |
Authors: Kapitonov,V.V. and Jurka,J. |
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Title: I-1_DR, a first example of vertebrate non-LTR retrotransposons that belong belong to the I clade. |
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Journal: Repbase Reports 2:(6) p. 18 (2002) |
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Abstract: I-1_DR is a non-LTR retrotransposon that belongs to the I clade. This element is characterized by 13-bp target site duplications. It can be an active element. It encodes two proteins: 417-aa I-1_DR1p (positions 3-1253) and 1250-aa I-1_DR2p (positions 1238-4987). These proteins are most close to corresponding proteins encoded by other I-like elements. I-1_DR1p is a putative RNA/DNA binding protein (it includes zinc-finger), and I-1_DR2p is composed of the AP endonuclease (aa positions 9-222), reverse transcriptase (positions 500-730) and RNaseH (positions 968-1095) domains. I-1_DR1p: MAASSGGGAVQAVGNDWIENGQEWGDGNDGSGNEVEEMEGSESCEPWTNCRGKKRKKRKNKLDSDEEMRS KVKEGNEEYNVFVRLVQEGATFEDWSPIQLTKALYKEIGEVRCAKKLRNGCLLVSCKDEAQQKKAIKVNK INGKKVKCSEVYDRKLIRGVITGIPVSESLNNVIEGITNAKIKEAKRLKTRWNGAICDSLSIMLTFDETK LPDKVFIGYMSYEVKMYIPPPVRCYKCQKYGHIAAICKGKMRCSKCSGEHEYGQCDKEAKLKCCNCGGEH SSAYRGCEVNKRMQEIQRIKVTQGISYAEATKKVRPTREQMGQMPTMREERKDMIKCKKCDKIKEETLIV DKNEFVLFMAEVINCSAQTTSRTERIKIIVKAAEKYMGIKGIPWESVRNTLNEEVQQQQSQAWGGVA I-1_DR2p: MGWSCIMVIFILQWNARSLISNGQEFKKYIDDLNEKPDIVCVQESWLISRLEFNIKGYNAVRMDRKIGKG GGIITFIKKGIQYREVKRGNELEYVIVEVWSSEGNIKIINFYNPCRLLEREQLEEIWEGINGKIIWCGDF NAHSTLWGNRNDNNGRVIEEFIEEEELVCINDGTGTRLNTARGTESAIDITIVTKDIADRCEWEVLRGNT VGSDHYPIKTQVGIECAKEIEVREEKWILERADWDKFREISEDLLQKIEDNLDVENMCKRISGGIIEAAK MAIPKSKPKIINKIVPWWTKECRKAIKERNKAFKKMKTTHNFQNLMKYKQAQAIVRKTVKKSKKEYWRQF CESIGRTTPVERVWGMIKKMKGNGKEYGYPMLMDGQRVIINNKEKAEIIARTLIKVHSTDNLSQEEKRGR VETYERYQFDLGKDDGDQVLNINFSGTELSRALKKLGKTAPGRDGICYTMLENLTDKGKEVLLKLYNKIW EVGVIPKEWKKAVIIPIKKPGKDPKQPTSYRPIALTSHIGKTMERMINDRLVYWVETKRKIGNYQSGFRK GRGTMDPILRLEDDIKKAQVNRESVIAVFLDIEKAYDMLWRDGVLIKLNQIGVKGRILRWVKEFLSERSI TVKINGTFSECYSVENGTPQGSIISPFLFSIMFDGIFKEIENNTGVALFADDGAIWKRGRNITFIMKKMQ QILNTVQEWTVKWGFRISQEKTKAMLFTKKKIREDLKLKLGGKDLENVESFKYLGVWFDRRLTWNTHISK MVDKCKRVLNVMRCLCGVDWGASRVALKSIYTGLIRSVIDYGCMVYGSAANTTLKQLDVIQNQALRVCCG AMKTTPVAALQVEMGEMPLHLRRDQLEVVYWANLKGHNENHIAQTVLMQCQEREKRGIKGYGWTIQQKIN DMEIDTIKISPTIVFPVVPTWLLDDLEVDFEIMKEKQENEIDSKQVENYIREKYSETTEIYTDASRIGQR VGVSFSIPKLKIEVTKRINNNLAVYTAELVAIWLALKWVEDNKPIKAVIASDSSSALISIKNVVSESRQD IIYEIVQLGNNIIKSGVIISLLWVPAHIGVSGNEMADKLAKQAAQQTMIDMDIKYSKSEIKSIVKTKILG KWQHIWNNGSTGRQYYTIQNIVGKGRETRKNKKEEDKFSRMRFNHTSLNSTLHMINKHADGMCECNNQET VEHVLMHCPIYQTERNILFTQLQEKQVEPNIKNILKLSTGDVCFRYVYNYLKDTGLINRI
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Derived: Positions 25824 31106 Accession No AL672145 GenBank |
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Download Sequence - Format: IG, EMBL, FASTA |
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References: |
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